Our new Clear+ tissue clearing method is the sole strategy that delipidates samples without having change in morphology and with nominal effect on structural integrity.
Our flip-important SmartBatch+ program combines electrophoretic tissue clearing and immunolabeling into one particular significant-throughput unit.
Antibodies may well acquire months to diffuse by only some millimeters of tissue, with a steep labeling gradient from surface to core.
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SE works by using a rotational electrical discipline to disperse very electromobile molecules (including antibodies or surfactant micelles) all through a porous sample without harming electrically billed constructions inside the tissue. This enables two-four working day clearing of intact organs,
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eFLASH is a swift tissue labeling method that permits for uniform whole-organ staining in 20 rounds of labeling.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed through intact tissue volumes, while its modular style and design enables you to enhance and customize particular person elements.
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Leverage the Clear+ tissue clearing approach, as well as eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label entire organs. Critical highlights and features consist of:
Our novel Defend tissue preservation strategy varieties intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.